Endocrine Abstracts

Low bone density in women with androgen insensitivity syndrome [AIS] has been attributed to both androgen and oestrogen deficiency. Tall stature in women with AIS has been attributed to the presence of the Y chromosome and to delayed closure of the epiphyses due to relative sex steroid deficiency. In order to gain greater insight into these interactions we have compared bone density and height in four groups of women-27 women with AIS, 15 women with 46XY gonadal dysgenesis, 25...

Objectives: To compare height and body proportions between women with complete androgen insensitivity syndrome (CAIS) and women with gonadal dysgenesis (GD).Design: Cross-sectional study of three groups of women with varying degrees of exposure to sex hormones and different combinations of sex chromosomes. Fourteen subjects had CAIS and 46XY (CAIS(XY)), aged (mean±S.E.M.) 42.1±2.8 years; seven had GD and 46XY (GD(XY)), aged 36.7&...

Aims: To compare bone mineral density (BMD) and stature between women with androgen insensitivity syndrome and women with gonadal dysgenesis.Settings: Adult Intersex Clinic.Design: Retrospective cross-sectional study of three groups of women aged 17-58 years with varying degrees of exposure to sex hormones and different combinations of sex chromosomes. Forty-six subjects had complete androgen insensitivity syndrome and 46XY [CAIS(X...